Bartter- and Gitelman-like syndromes: salt-losing tubulopathies with loop or DCT defects

Thu, Nov 10, 2011

Uncategorized

The pregnancy of a 28-year-old woman with one previous miscarriage is complicated by idiopathic polyhydramnios, which was first recognized by routine ultrasound at the end of the second trimester. After therapeutic amniocentesis (estimated amniotic fluid volume of 10 l) and rupture of membranes at 30 weeks of gestation, an acute Caesarean section was performed. The delivered male infant was appropriate for gestational age and showed an uneventful postnatal adaptation, except for a mild respiratory distress syndrome requiring a positive end-expiratory pressure device. However, a few days later, he developed hyponatremia, hyperkalemia, hyposthenuria, hypercalciuria, and a weight loss from birthweight by >15%. The diagnosis most likely is:






What is the most appropriate pharmacotherapeutic intervention in a patient with polyuric and hypercalciuric salt-losing tubulopathy associated with hyperaldosteronism?






Which patient with a salt-losing tubulopathy is most likely at risk to develop end-stage renal failure later in life?






Which special subtype of salt-losing tubulopathy is least likely to be associated with chronic hypercalciuria and nephrocalcinosis?





What is the most convenient way to differentiate between renal and extrarenal salt losses?





What is the most unlikely complication or sequelae of a DCT disorder with an apical uptake defect (GS)?








 
 

Renal amyloidosis in children

Thu, Nov 10, 2011

Uncategorized

The main cause of childhood amyloidosis is






Which of the answers below is wrong regarding  autoinflammatory diseases causing secondary amyloidosis in children?






Which of the following is NOT associated with secondary amyloidosis in FMF?






Which of the answers below  is WRONG about the treatment of amyloidosis?






What is the MOST common initial manifestation of renal disease secondary to amyloidosis?








 
 

Nocturnal enuresis—theoretic background and practical guidelines

Thu, Nov 10, 2011

Uncategorized

Should a 5-year-old child be actively treated for enuresis?





Why should imipramine not be a first-line therapy of enuresis?





Why is the enuresis alarm recommended as a first-line therapy in enuresis?






Which of the following factors is not implicated by modern research as crucial in the pathogenesis of enuresis?








 
 

22nd Medical & Nursing Annual Congress of the European Society of Paediatric and Neonatal Intensive Care

Mon, Apr 4, 2011

Congresses

November 2, 2011toNovember 5, 2011

Location: Hannover, Germany

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ESPNIC 2011 dedicated to promoting and advancing the art and science of paediatric and neonatal intensive care. Major topics to be addressed include: heart surgery, pain control and sedation, monitoring and influencing the immune system, organ support/organ replacements, neonatal respiratory failure, quality and performance improvement, critical care pharmacology, resuscitation, and brain protection.

For more information: http://www.kenes.com/espnic

 
 

Event Calendar

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